Three of the four characters are equipped with a melee weapon: a katana for Linn, a bladed naginata staff for the Hunter, and an extendable-retractable spear/staff for the Warrior. Four characters are available for the players' use: two cyborg soldiers, Major Dutch Schaefer and Lieutenant Linn Kurosawa and two Predators, a Hunter and a Warrior.
The default cabinet for the game allows as many as three players to play simultaneously, although some smaller cabinets only accommodate two players. Predator uses a control setup with an eight-directional joystick and three buttons: one to attack, one to jump, and one to shoot.